发明申请
- 专利标题： ANTI-SCLEROSTIN ANTIBODIES
- 专利标题（中）： 抗沙门氏菌抗体
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申请号： US12160472申请日： 2008-03-11
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公开(公告)号： US20090060924A1公开(公告)日： 2009-03-05
- 发明人: Andrew Ihor Korytko , David Matthew Marquis , Eric Michael Smith , Barbara Anne Swanson
- 申请人： Andrew Ihor Korytko , David Matthew Marquis , Eric Michael Smith , Barbara Anne Swanson
- 国际申请： PCT/US08/56527 WO 20080311
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/18 ; A61P19/00
摘要：
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
公开/授权文献
- US07744874B2 Anti-sclerostin antibodies 公开/授权日：2010-06-29
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