发明申请
- 专利标题: Array-based method for performing SNP analysis
- 专利标题(中): 用于执行SNP分析的基于阵列的方法
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申请号: US11897613申请日: 2007-08-31
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公开(公告)号: US20090062138A1公开(公告)日: 2009-03-05
- 发明人: Bo U. Curry , Nicholas M. Sampas , Robert A. Ach
- 申请人: Bo U. Curry , Nicholas M. Sampas , Robert A. Ach
- 主分类号: C40B30/04
- IPC分类号: C40B30/04 ; C40B40/06
摘要:
An array-based method for performing SNP analysis is provided. In certain embodiments, the method may comprise: a) contacting a labeled genomic sample with an array comprising a first SNP-detecting oligonucleotide and a second SNP-detecting oligonucleotide that differ from each other by a single nucleotide, under hybridization conditions that provide binding equilibrium; and b) evaluating a SNP of said labeled genomic sample by comparing: i. binding of the labeled genomic sample to the first SNP-detecting oligonucleotide and ii. binding of the labeled genomic sample to said second SNP-detecting oligonucleotide.
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