发明申请
- 专利标题： PYRIDOPYRIMIDINE PROTEIN TYROSINE PHOSPHATASE INHIBITORS
- 专利标题（中）： 吡啶酮嘧啶蛋白酪氨酸磷酸酶抑制剂
-
申请号： US12259737申请日： 2008-10-28
-
公开(公告)号： US20090062276A1公开(公告)日： 2009-03-05
- 发明人: Steven Joseph Berthel , Adrian Wai-Hing Cheung , Kyungjin Kim , Shiming Li , Kshitij Chhabilbhai Thakkar , Weiya Yun
- 申请人： Steven Joseph Berthel , Adrian Wai-Hing Cheung , Kyungjin Kim , Shiming Li , Kshitij Chhabilbhai Thakkar , Weiya Yun
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D471/04 ; A61P3/10 ; A61K31/5377
摘要：
The present invention comprises pyridopyrimidinediamine compounds of the general formula I: The compounds of the present invention are potent inhibitors of PTP1B. Accordingly, the invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.
公开/授权文献
- US2281754A Heat exchanger 公开/授权日：1942-05-05
信息查询
IPC分类:
