Invention Application
- Patent Title: METHODS OF IDENTIFYING LEAD COMPOUNDS THAT MODULATE TOXICITY OF NEUROTOXIC POLYPEPTIDES
- Patent Title (中): 识别神经毒性多肽的毒性的铅化合物的方法
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Application No.: US12272031Application Date: 2008-11-17
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Publication No.: US20090068111A1Publication Date: 2009-03-12
- Inventor: Paul J. Muchowski , Susan L. Lindquist , Tiago Outeiro
- Applicant: Paul J. Muchowski , Susan L. Lindquist , Tiago Outeiro
- Applicant Address: US WA Seattle US MA Cambridge
- Assignee: UNIVERSITY OF WASHINGTON,WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
- Current Assignee: UNIVERSITY OF WASHINGTON,WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
- Current Assignee Address: US WA Seattle US MA Cambridge
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12Q1/02 ; C12N1/19
Abstract:
Methods of screening candidate agents to identify lead compounds for the development of therapeutic agents for the treatment of a neurodegenerative disease, such as Huntington's Disease and Parkinson's Disease and methods for identifying a mutation in, or changes in expression of, a gene associated with neurodegenerative disease, such as Huntington's Disease and Parkinson's Disease, are provided.
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