发明申请
US20090068718A1 AMINO ACID DERIVATIVES OF INDOLINONE BASED PROTEIN KINASE INHIBITORS
审中-公开
基于吲哚宁酮的蛋白激酶抑制剂的氨基酸衍生物
- 专利标题: AMINO ACID DERIVATIVES OF INDOLINONE BASED PROTEIN KINASE INHIBITORS
- 专利标题(中): 基于吲哚宁酮的蛋白激酶抑制剂的氨基酸衍生物
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申请号: US12159579申请日: 2006-12-28
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公开(公告)号: US20090068718A1公开(公告)日: 2009-03-12
- 发明人: Congxin Liang , Yangbo Feng
- 申请人: Congxin Liang , Yangbo Feng
- 国际申请: PCT/US2006/049406 WO 20061228
- 主分类号: C12N9/99
- IPC分类号: C12N9/99 ; C07D405/06 ; C07D413/14
摘要:
Amino acid derivatives of pyrrolyl-indolinones and their amide or ester derivatives have enhanced and unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as cancer.
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