发明申请
- 专利标题: TRICYCLIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS
- 专利标题(中): 三氯化合物有效处理铁损
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申请号: US12044731申请日: 2008-03-07
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公开(公告)号: US20090069408A1公开(公告)日: 2009-03-12
- 发明人: Mikhail Chafeev , Nagasree Chakka , Jean-Jacques Cadieux , Jianmin Fu , Rajender Kamboj , Vishnumurthy Kodumuru , Jonathan Langille , Shifeng Liu , Jianyu Sun , Serguei Sviridov , Zaihui Zhang
- 申请人: Mikhail Chafeev , Nagasree Chakka , Jean-Jacques Cadieux , Jianmin Fu , Rajender Kamboj , Vishnumurthy Kodumuru , Jonathan Langille , Shifeng Liu , Jianyu Sun , Serguei Sviridov , Zaihui Zhang
- 申请人地址: CA Burnaby
- 专利权人: XENON PHARMACEUTICALS INC.
- 当前专利权人: XENON PHARMACEUTICALS INC.
- 当前专利权人地址: CA Burnaby
- 主分类号: A61K31/381
- IPC分类号: A61K31/381 ; C07D333/76 ; A61K31/343 ; C07D307/91 ; C07C257/10 ; A61K31/155
摘要:
This invention is directed to, for example, compounds of formula (I): wherein n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.
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