Invention Application
- Patent Title: TRICYCLIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS
- Patent Title (中): 三氯化合物有效处理铁损
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Application No.: US12044731Application Date: 2008-03-07
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Publication No.: US20090069408A1Publication Date: 2009-03-12
- Inventor: Mikhail Chafeev , Nagasree Chakka , Jean-Jacques Cadieux , Jianmin Fu , Rajender Kamboj , Vishnumurthy Kodumuru , Jonathan Langille , Shifeng Liu , Jianyu Sun , Serguei Sviridov , Zaihui Zhang
- Applicant: Mikhail Chafeev , Nagasree Chakka , Jean-Jacques Cadieux , Jianmin Fu , Rajender Kamboj , Vishnumurthy Kodumuru , Jonathan Langille , Shifeng Liu , Jianyu Sun , Serguei Sviridov , Zaihui Zhang
- Applicant Address: CA Burnaby
- Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee Address: CA Burnaby
- Main IPC: A61K31/381
- IPC: A61K31/381 ; C07D333/76 ; A61K31/343 ; C07D307/91 ; C07C257/10 ; A61K31/155

Abstract:
This invention is directed to, for example, compounds of formula (I): wherein n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.
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