发明申请
US20090074661A1 ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
审中-公开
抗IL-22RA抗体和结合合作伙伴及其在炎症中的使用方法
- 专利标题： ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
- 专利标题（中）： 抗IL-22RA抗体和结合合作伙伴及其在炎症中的使用方法
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申请号： US12177029申请日： 2008-07-21
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公开(公告)号： US20090074661A1公开(公告)日： 2009-03-19
- 发明人: Wenfeng Xu , Wayne Kindsvogel , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret D. Moore
- 申请人： Wenfeng Xu , Wayne Kindsvogel , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret D. Moore
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/18 ; A61K51/10 ; C12N5/12 ; A61P29/00
摘要：
The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
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