发明申请
- 专利标题： Acidic Insulin Preparations Having Improved Stability
- 专利标题（中）： 具有改善稳定性的酸性胰岛素制剂
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申请号： US12328208申请日： 2008-12-04
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公开(公告)号： US20090082255A1公开(公告)日： 2009-03-26
- 发明人: Anette Brunner-Schwarz , Norbert Lill
- 申请人： Anette Brunner-Schwarz , Norbert Lill
- 申请人地址： DE Frankfurt am Main
- 专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人地址： DE Frankfurt am Main
- 优先权： DE10227232.8 20020618
- 主分类号： A61K38/28
- IPC分类号： A61K38/28 ; A61P3/10
摘要：
The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally a preservative or combinations of two or more preservatives; and optionally an isotonicizing agent, buffers or further excipients or combinations thereof, the pharmaceutical formulation having a pH in the acidic range.
公开/授权文献
- US07713930B2 Acidic insulin preparations having improved stability 公开/授权日：2010-05-11
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