发明申请
US20090082975A1 METHOD OF SELECTING AN ACTIVE OLIGONUCLEOTIDE PREDICTIVE MODEL
审中-公开
选择活性寡核苷酸预测模型的方法
- 专利标题： METHOD OF SELECTING AN ACTIVE OLIGONUCLEOTIDE PREDICTIVE MODEL
- 专利标题（中）： 选择活性寡核苷酸预测模型的方法
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申请号： US12237330申请日： 2008-09-24
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公开(公告)号： US20090082975A1公开(公告)日： 2009-03-26
- 发明人: Tamara Balac Sipes , Susan M. Freier , Kenneth Dobie
- 申请人： Tamara Balac Sipes , Susan M. Freier , Kenneth Dobie
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 主分类号： G01N33/48
- IPC分类号： G01N33/48
摘要：
The present invention provides a method of identifying a predictor of antisense oligonucleotide activity by identifying properties of oligonucleotides, evaluating oligonucleotide activity of the oligonucleotides, and correlating oligonucleotide activity with the properties. A high correlation between oligonucleotide activity and a property indicates that the property is a predictor of oligonucleotide activity.
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