发明申请
- 专利标题： Indole Orexin Receptor Antagonists
- 专利标题（中）： 吲哚矿物质受体拮抗剂
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申请号： US12085342申请日： 2006-11-17
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公开(公告)号： US20090088452A1公开(公告)日： 2009-04-02
- 发明人: Paul J. Coleman , Anthony J. Roecker , Jeffrey M. Bergman
- 申请人： Paul J. Coleman , Anthony J. Roecker , Jeffrey M. Bergman
- 国际申请： PCT/US06/44526 WO 20061117
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; C07D401/14 ; A61K31/4427 ; C07D417/14 ; A61K31/433 ; A61K31/427 ; C07D413/14 ; A61K31/422
摘要：
The present invention is directed to substituted indole compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.