发明申请
- 专利标题： 3-Arylamino pyridine derivatives
- 专利标题（中）： 3-芳基氨基吡啶衍生物
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申请号： US11665651申请日： 2005-10-19
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公开(公告)号： US20090093462A1公开(公告)日： 2009-04-09
- 发明人: Ulricn Abel , Holger Deppe , Achim Feurer , Ulrich Gradler , Kerstin Otte , Renate Sekul , Meinolf Thiemann , Andreas Goutopoulos , Matthias Schwarz , Xuliang Jiang
- 申请人： Ulricn Abel , Holger Deppe , Achim Feurer , Ulrich Gradler , Kerstin Otte , Renate Sekul , Meinolf Thiemann , Andreas Goutopoulos , Matthias Schwarz , Xuliang Jiang
- 优先权： EP04024967.4 20041020
- 国际申请： PCT/EP05/11257 WO 20051019
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D405/12 ; C07D213/72 ; C07D413/12 ; C07D401/12 ; A61P29/00 ; A61K31/4545 ; A61K31/55 ; A61K31/506 ; A61K31/4439 ; A61K31/5377 ; A61P25/00 ; A61P17/00 ; C07D413/04 ; A61K31/443
摘要：
The invention provides novel, substituted 3-arylamino pyridine compounds (I) pharmaceutically acceptable salts, solvates and prodrug compounds thereof, wherein W, R1, R2, R9, R10, R11, R12, R13, R14 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Also disclosed is the use of such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and pharmaceutical compositions containing such compounds.
公开/授权文献
- US07956191B2 3-arylamino pyridine derivatives 公开/授权日：2011-06-07