Invention Application
- Patent Title: PREPARATION OF PHARMACEUTICAL SALTS OF PIPERAZINE COMPOUNDS
- Patent Title (中): 哌嗪化合物的药用盐的制备
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Application No.: US12331948Application Date: 2008-12-10
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Publication No.: US20090093496A1Publication Date: 2009-04-09
- Inventor: Wenxue Wu , Loc Thanh Tran , Bosco D'Sa , Feng Liang , William Leong , Hong-Chang Lee , Kevin Klopfer , Vijay Sabesan
- Applicant: Wenxue Wu , Loc Thanh Tran , Bosco D'Sa , Feng Liang , William Leong , Hong-Chang Lee , Kevin Klopfer , Vijay Sabesan
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D401/14
Abstract:
The present invention is generally directed to a process to directly prepare pharmaceutically acceptable salts enriched with respect to selected rotameric salts of a basic compound, by creative choice of an acid and a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance of a rotamer.
Information query
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