发明申请
- 专利标题: Pharmaceutical composition
- 专利标题(中): 药物组成
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申请号: US12158413申请日: 2006-12-18
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公开(公告)号: US20090093499A1公开(公告)日: 2009-04-09
- 发明人: Miha Tomaz Jaklic , Klemen Naversnik
- 申请人: Miha Tomaz Jaklic , Klemen Naversnik
- 申请人地址: SI SI Ljubljana
- 专利权人: LEK PHARMACEUTICALS D.D.
- 当前专利权人: LEK PHARMACEUTICALS D.D.
- 当前专利权人地址: SI SI Ljubljana
- 优先权: SIP200500344 20051220
- 国际申请: PCT/EP2006/012180 WO 20061218
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; A61P3/06
摘要:
A chemically stable formulation of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically-acceptable salt thereof for oral use, such as tablets, capsules, powders, granules has been developed using the substances which stabilize against formation of degradation products: lactone and oxidation product.
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