发明申请
US20090099160A1 4-(4-(Imidazol-4-Yl) Pyrimidin-2-Ylamino) Benzamides as CDK Inhibitors
审中-公开
4-(4-(咪唑-4-基)嘧啶-2-基氨基)苯甲酰胺作为CDK抑制剂
- 专利标题: 4-(4-(Imidazol-4-Yl) Pyrimidin-2-Ylamino) Benzamides as CDK Inhibitors
- 专利标题(中): 4-(4-(咪唑-4-基)嘧啶-2-基氨基)苯甲酰胺作为CDK抑制剂
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申请号: US11793254申请日: 2005-12-15
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公开(公告)号: US20090099160A1公开(公告)日: 2009-04-16
- 发明人: David Andrews , Maurice Raymond Finlay , Clive Green , Clifford Jones
- 申请人: David Andrews , Maurice Raymond Finlay , Clive Green , Clifford Jones
- 优先权: GB0427699.4 20041217; GB0515740.9 20050730
- 国际申请: PCT/GB05/04865 WO 20051215
- 主分类号: A61K31/506
- IPC分类号: A61K31/506 ; C07D403/04 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; A61K31/541 ; A61K31/5377 ; C07D417/14 ; C07D409/14 ; A61P35/00
摘要:
Compounds of the formula (I): wherein variable groups are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.