- 专利标题： Compounds, Compositions and Methods
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申请号： US12238313申请日： 2008-09-25
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公开(公告)号： US20090099198A1公开(公告)日： 2009-04-16
- 发明人: Bradley Paul Morgan , Alex Muci , Pu-Ping Lu , Erica Anne Kraynack , Todd Tochimoto , David J. Morgans, Jr.
- 申请人： Bradley Paul Morgan , Alex Muci , Pu-Ping Lu , Erica Anne Kraynack , Todd Tochimoto , David J. Morgans, Jr.
- 专利权人： Cytokinetics, Inc.
- 当前专利权人： Cytokinetics, Inc.
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D401/12
摘要：
Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
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