发明申请
- 专利标题： SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS
- 专利标题（中）： 丝氨酸蛋白激酶和PARP调节剂
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申请号： US11849230申请日： 2007-08-31
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公开(公告)号： US20090105233A1公开(公告)日： 2009-04-23
- 发明人: Peter C. CHUA , Fabrice Pierre , Jeffrey P. Whitten
- 申请人： Peter C. CHUA , Fabrice Pierre , Jeffrey P. Whitten
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D471/04 ; C07D413/14 ; C07D495/04 ; A61K31/4365 ; A61K31/538 ; A61P35/00 ; A61K31/541 ; A61K31/5377 ; C07D279/12 ; C12Q1/02
摘要：
The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate casein kinase (CK) activity and/or poly(ADP-ribose)polymerase (PARP) activity. The invention also relates in part to methods for using such molecules.