发明申请
- 专利标题： EP4 Receptor Agonist, Compositions and Methods Thereof
- 专利标题（中）： EP4受体激动剂，组合物和方法
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申请号： US11989643申请日： 2006-07-28
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公开(公告)号： US20090105234A1公开(公告)日： 2009-04-23
- 发明人: John Colucci , Yongxin Han , Julie A. Farand
- 申请人： John Colucci , Yongxin Han , Julie A. Farand
- 国际申请： PCT/CA2006/001243 WO 20060728
- 主分类号： A61K31/5355
- IPC分类号： A61K31/5355 ; C07D413/06 ; A61P27/02
摘要：
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions, which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modeling and remodeling processes of the osteoblasts and osteoclasts.
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