发明申请
US20090105252A1 Pyrimidine Derivatives and Their Use in Therapy as well as the Use of Pyrimidine Derivatives in the Manufacture of a Medicament for Prevention and/or Treatment of Alzheimer's Disease
审中-公开
嘧啶衍生物及其在治疗中的应用以及嘧啶衍生物在制造预防和/或治疗阿尔茨海默病药物中的应用
- 专利标题： Pyrimidine Derivatives and Their Use in Therapy as well as the Use of Pyrimidine Derivatives in the Manufacture of a Medicament for Prevention and/or Treatment of Alzheimer's Disease
- 专利标题（中）： 嘧啶衍生物及其在治疗中的应用以及嘧啶衍生物在制造预防和/或治疗阿尔茨海默病药物中的应用
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申请号： US12089008申请日： 2006-10-02
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公开(公告)号： US20090105252A1公开(公告)日： 2009-04-23
- 发明人: Lars Andersson , Erwan Arzel , Stefan Berg , Jeremy Burrows , Sven Hellberg , Fernando Huerta , Torben Pedersen , Tobias Rein , Didier Rotticci , Karin Staaf , Dominika Turek
- 申请人： Lars Andersson , Erwan Arzel , Stefan Berg , Jeremy Burrows , Sven Hellberg , Fernando Huerta , Torben Pedersen , Tobias Rein , Didier Rotticci , Karin Staaf , Dominika Turek
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 优先权： SE0502174-6 20051003
- 国际申请： PCT/SE2006/001116 WO 20061002
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D403/02 ; A61K31/506 ; C07D413/14 ; A61P25/28 ; C07D403/14 ; A61K31/496
摘要：
Compounds of formula I wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification as a base or a pharmaceutically acceptable salt, solvate or solvate of salt thereof, processes for their preparation, new intermediates used therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.
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