发明申请
- 专利标题: Pharmaceutical Agent
- 专利标题(中): 药剂
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申请号: US12227359申请日: 2007-05-14
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公开(公告)号: US20090105314A1公开(公告)日: 2009-04-23
- 发明人: Masayuki Ii , Hideyasu Matsuda , Kouji Mouri
- 申请人: Masayuki Ii , Hideyasu Matsuda , Kouji Mouri
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 优先权: JP2006-135883 20060515
- 国际申请: PCT/JP2007/059908 WO 20070514
- 主分类号: A61K31/24
- IPC分类号: A61K31/24 ; A61K31/4192 ; A61K31/4196 ; A61K31/428 ; A61P9/00
摘要:
The present invention provides an agent for the prophylaxis or treatment of complications after coronary-artery bypass surgery or cardiac diseases, autoimmune diseases, central nervous system diseases, inflammatory diseases, sepsis, severe sepsis or septic shock in a patient who undergoes coronary-artery bypass surgery, which comprises a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a compound represented by the formula (II): wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof, and an agent for the prophylaxis or treatment of sepsis and the like, as well as complications after coronary-artery bypass surgery, which is prepared for administration of ethyl (6R)-6-[(2-chloro-4-fluoroanilino)sulfonyl]-1-cyclohexene-1-carboxylate or a salt thereof or a prodrug thereof in a specific dose at a specific administration time.