发明申请
- 专利标题： METHODS FOR EVALUATING GENETIC SUSCEPTIBILITY AND THERAPY FOR CHRONIC INFLAMMATORY DISEASES
- 专利标题（中）： 评估慢性炎性疾病遗传易感性和治疗方法
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申请号： US12352460申请日： 2009-01-12
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公开(公告)号： US20090117046A1公开(公告)日： 2009-05-07
- 发明人: Yoram GRONER , David Bettoun
- 申请人： Yoram GRONER , David Bettoun
- 专利权人： YEDA RESEARCH AND DEVELOPMENT, LTD.
- 当前专利权人： YEDA RESEARCH AND DEVELOPMENT, LTD.
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; C12Q1/68 ; A61P43/00
摘要：
The invention discloses a knockout mouse that is homozygous for a RUNX3 null allele, as a novel model for chronic inflammatory disease. The present invention provides methods of diagnosing and assessing predisposition to chronic inflammatory diseases. The present invention further provides methods for testing agents for effectiveness in treating and/or preventing diseases associated with chronic inflammatory or autoimmune conditions.
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