发明申请
US20090118159A1 HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES
有权
用于治疗糖尿病的GLK激活剂的异氟烷苯甲酸衍生物
- 专利标题: HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES
- 专利标题(中): 用于治疗糖尿病的GLK激活剂的异氟烷苯甲酸衍生物
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申请号: US11995077申请日: 2006-07-03
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公开(公告)号: US20090118159A1公开(公告)日: 2009-05-07
- 发明人: Darren McKerrecher , Kurt Gordon Pike , Michael James Waring
- 申请人: Darren McKerrecher , Kurt Gordon Pike , Michael James Waring
- 优先权: GB0514173.4 20050709; GB0516297.9 20050809; GB0523862.1 20051124; GB0524589.9 20051202; GB0607977.6 20060422
- 国际申请: PCT/GB06/02471 WO 20060703
- 主分类号: A61K31/497
- IPC分类号: A61K31/497 ; C07D403/14 ; A61P3/04 ; A61P3/10 ; A61K38/28
摘要:
Compounds of formula (I) wherein R1, HET-1 and HET-2 are as described in the specification, and their salts and pro-drugs, are activators of glucokinase (GLK) and are thereby useful in the treatment of, for example, type 2 diabetes. Processes for preparing compounds of formula (I) are also described.
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