发明申请
- 专利标题： Novel Benzopyran Derivatives Having Inhibitory Activities Against Liver Fibrosis and Cirrhosis and Their Pharmaceutical Uses
- 专利标题（中）： 具有抑制肝纤维化和肝硬化及其药物用途的新型苯并吡喃衍生物
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申请号： US11794564申请日： 2005-06-15
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公开(公告)号： US20090118302A1公开(公告)日： 2009-05-07
- 发明人: Young-Dae Gong , Jin-Soo Seo , Moon-Kook Jeon , Wei-Jong Kwak , Yong-Baik Cho , Nam Kyu Lee , Eun Ju Lee , Jung Bum Lee , Jun Won Lee , Sukho Lee , Mi-Sook Dong , Jeong-Ran Kim
- 申请人： Young-Dae Gong , Jin-Soo Seo , Moon-Kook Jeon , Wei-Jong Kwak , Yong-Baik Cho , Nam Kyu Lee , Eun Ju Lee , Jung Bum Lee , Jun Won Lee , Sukho Lee , Mi-Sook Dong , Jeong-Ran Kim
- 优先权： KR10-2004-0117707 20041231; KR10-2004-0117711 20041231
- 国际申请： PCT/KR05/01833 WO 20050615
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D311/58 ; A61K31/352 ; A61P1/16 ; A61P17/00 ; A61P9/00 ; A61P11/00 ; A61K31/453 ; C07D405/12
摘要：
The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-β receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof.
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