发明申请
- 专利标题: Purification of pegylated polypeptides
- 专利标题(中): 聚乙二醇化多肽的纯化
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申请号: US12218545申请日: 2008-07-16
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公开(公告)号: US20090118476A1公开(公告)日: 2009-05-07
- 发明人: Josef Burg , Klaus Reichert , Axel Schroth , Hartmut Schurig , Axel Wessner
- 申请人: Josef Burg , Klaus Reichert , Axel Schroth , Hartmut Schurig , Axel Wessner
- 优先权: EP07013959.7 20070717
- 主分类号: C07K1/18
- IPC分类号: C07K1/18
摘要:
The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form.
公开/授权文献
- US08138317B2 Purification of pegylated polypeptides 公开/授权日:2012-03-20
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