- 专利标题： PROCESS FOR PREPARING ACYCLIC HCV PROTEASE INHIBITORS
-
申请号： US12355157申请日： 2009-01-16
-
公开(公告)号： US20090124809A1公开(公告)日： 2009-05-14
- 发明人: Carl Alan BUSACCA , Rogelio Perez FRUTOS , Nizar HADDAD , Suresh R. KAPADIA , Jon Charles LORENZ , Anjan SAHA , Chris Hugh SENANAYAKE , Xudong WEI
- 申请人： Carl Alan BUSACCA , Rogelio Perez FRUTOS , Nizar HADDAD , Suresh R. KAPADIA , Jon Charles LORENZ , Anjan SAHA , Chris Hugh SENANAYAKE , Xudong WEI
- 申请人地址： DE Ingelheim
- 专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人地址： DE Ingelheim
- 主分类号： C07D417/14
- IPC分类号： C07D417/14 ; C07C225/22
摘要：
Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula: and halogenated or sulfonated bromoquinoline compounds.
公开/授权文献
- US08017771B2 Process for preparing acyclic HCV protease inhibitors 公开/授权日：2011-09-13
信息查询
