发明申请
- 专利标题: P38 Kinase Inhibiting Agents
- 专利标题(中): P38激酶抑制剂
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申请号: US11990050申请日: 2006-08-08
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公开(公告)号: US20090131472A1公开(公告)日: 2009-05-21
- 发明人: Meng-Hsin Chen , James B. Doherty , Robert Tynebor , Swaminathan R. Natarajan , Zhen Li , Soumya P. Sahoo
- 申请人: Meng-Hsin Chen , James B. Doherty , Robert Tynebor , Swaminathan R. Natarajan , Zhen Li , Soumya P. Sahoo
- 国际申请: PCT/US2006/030962 WO 20060808
- 主分类号: A61K31/4375
- IPC分类号: A61K31/4375 ; C07D455/02 ; A61P37/02
摘要:
Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: (I) are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.
公开/授权文献
- US07879875B2 P38 kinase inhibiting agents 公开/授权日:2011-02-01