发明申请
US20090131527A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME
审中-公开
新型硫代酸衍生物和含有其的氯离子通道阻断剂
- 专利标题: NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME
- 专利标题(中): 新型硫代酸衍生物和含有其的氯离子通道阻断剂
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申请号: US12022405申请日: 2008-01-30
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公开(公告)号: US20090131527A1公开(公告)日: 2009-05-21
- 发明人: Changjoon Justin Lee , Eun-Joo Roh , Soo-Jin Oh , Jung-Hwan Park , Jae-Kyun Lee
- 申请人: Changjoon Justin Lee , Eun-Joo Roh , Soo-Jin Oh , Jung-Hwan Park , Jae-Kyun Lee
- 申请人地址: KR Seoul
- 专利权人: Korea Institute of Science and Technology
- 当前专利权人: Korea Institute of Science and Technology
- 当前专利权人地址: KR Seoul
- 优先权: KR10-2007-0117886 20071119
- 主分类号: A61K31/196
- IPC分类号: A61K31/196 ; C07C229/58 ; C07C227/18 ; C12Q1/02 ; A61P29/00 ; A61P35/00
摘要:
The present invention relates to novel anthranilic acid derivatives represented by Chemical Formula I, and a chloride channel blocking agent containing the anthranilic acid derivative or its pharmacologically acceptable salts as an active ingredient. In another aspect, the present invention relates to a method of accurately and efficiently detecting the intracellular chloride channel inhibition and method of screening a chloride channel blocking agent.
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