发明申请
- 专利标题: Inducible SIRNA expression cassette and method of use
- 专利标题(中): 诱导性SIRNA表达盒和使用方法
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申请号: US11814158申请日: 2006-01-18
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公开(公告)号: US20090133136A1公开(公告)日: 2009-05-21
- 发明人: Demin Zhou , Jon E. Chatterton , Ning Ke , Jing Zhang , Joshua Bliesath , Henry Li , Flossie Wong-Staal
- 申请人: Demin Zhou , Jon E. Chatterton , Ning Ke , Jing Zhang , Joshua Bliesath , Henry Li , Flossie Wong-Staal
- 申请人地址: US CA San Diego
- 专利权人: Immusol Incorporated
- 当前专利权人: Immusol Incorporated
- 当前专利权人地址: US CA San Diego
- 国际申请: PCT/US06/01997 WO 20060118
- 主分类号: A01K67/027
- IPC分类号: A01K67/027 ; C12N15/82 ; C12N15/85 ; A61K48/00 ; C40B40/06 ; C12N5/10
摘要:
An inducible siRNA expression polynucleotide and methods for its use are provided. The expression polynucleotide comprises a bicistronic expression cassette that encodes a repressor and a detectable marker, wherein the repressor controls expression of siRNA expression in the absence of an inducer.