发明申请
- 专利标题： Drug Carrier
- 专利标题（中）： 药品承运人
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申请号： US11886319申请日： 2006-03-10
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公开(公告)号： US20090136443A1公开(公告)日： 2009-05-28
- 发明人: Shinji Takeoka , Yosuke Okamura , Hideo Kanazawa , Shuji Hisamoto , Kohei Kubota , Yosuke Obata
- 申请人： Shinji Takeoka , Yosuke Okamura , Hideo Kanazawa , Shuji Hisamoto , Kohei Kubota , Yosuke Obata
- 申请人地址： JP Tokyo JP Shinjuku-Ku
- 专利权人： Oxgenix Co., Ltd.,WASEDA UNIVERSITY
- 当前专利权人： Oxgenix Co., Ltd.,WASEDA UNIVERSITY
- 当前专利权人地址： JP Tokyo JP Shinjuku-Ku
- 优先权： JP2005-075663 20050316; JP2005-252366 20050831
- 国际申请： PCT/JP06/05304 WO 20060310
- 主分类号： A61K31/787
- IPC分类号： A61K31/787 ; A61K31/785 ; C08G63/91
摘要：
The present invention has an object of providing a drug carrier capable of controlling in vivo pharmacokinetics. The present invention is directed to a drug carrier comprising a molecular assembly having a drug incorporated therein, and the above object can be achieved by a part of the amphiphilic molecules included in the molecular assembly being released from the molecular assembly by an external environmental change. The present invention utilizes a phenomenon that the hydrophilic-hydrophobic balance of the amphiphilic molecules is shifted toward hydrophilicity by an external environmental change and thus the amphiphilic molecules are freed from the molecular assembly.
公开/授权文献
- US08647613B2 Drug carrier 公开/授权日：2014-02-11
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