发明申请
US20090136986A1 METHODS AND CELLS FOR CREATING FUNCTIONAL DIVERSITY AND USES THEREOF
审中-公开
用于创建功能多样性的方法和细胞及其用途
- 专利标题： METHODS AND CELLS FOR CREATING FUNCTIONAL DIVERSITY AND USES THEREOF
- 专利标题（中）： 用于创建功能多样性的方法和细胞及其用途
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申请号： US12273098申请日： 2008-11-18
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公开(公告)号： US20090136986A1公开(公告)日： 2009-05-28
- 发明人: George Church , Brian M. Baynes
- 申请人： George Church , Brian M. Baynes
- 申请人地址： US MA Cambridge
- 专利权人： Codon Devices, Inc.
- 当前专利权人： Codon Devices, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; C12N15/74
摘要：
The invention provides methods and compositions relating to cells having altered functions, and the nucleic acids that impart those functions. Altered cellular function arises from in vivo directed recombination of genetic elements to yield a recombined nucleic acid. These methods and compositions may utilize altered host cells having altered recombination enzyme profiles and/or altered recombination sites. The invention involves in some aspects methods for assembling nucleic acid molecules, such as genomic DNA. Aspects of the invention also provide kits, compositions, devices, and systems for generating novel recombined nucleic acids and cells having altered cell function.
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