Invention Application
- Patent Title: Heterobicyclic metalloprotease inhibitors
- Patent Title (中): 异双环金属蛋白酶抑制剂
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Application No.: US12001043Application Date: 2007-12-07
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Publication No.: US20090137547A1Publication Date: 2009-05-28
- Inventor: Christoph Steeneck , Christian Gege , Frank Riohter , Holko Kroth , Mouhlee Hochgueriel , Michael Essors , Joshua Van Veldhulzen , Bert Nolte , Brian M. Gallaghor, JR. , Tim Feuerstein , Matthias Schneider , Toralen Arndt , Hongbo Deng , Ralf Blesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholelld , Arthur G. Taverse
- Applicant: Christoph Steeneck , Christian Gege , Frank Riohter , Holko Kroth , Mouhlee Hochgueriel , Michael Essors , Joshua Van Veldhulzen , Bert Nolte , Brian M. Gallaghor, JR. , Tim Feuerstein , Matthias Schneider , Toralen Arndt , Hongbo Deng , Ralf Blesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholelld , Arthur G. Taverse
- Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee: Alantos Pharmaceuticals Holding, Inc.
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; C07D487/04 ; A61K31/519
Abstract:
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
Public/Granted literature
- US07795245B2 Heterobicyclic metalloprotease inhibitors Public/Granted day:2010-09-14
Information query
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