发明申请
US20090142272A1 Pfks as modifiers of the igfr pathway and methods of use
审中-公开
Pfks作为igfr途径的修饰剂和使用方法
- 专利标题： Pfks as modifiers of the igfr pathway and methods of use
- 专利标题（中）： Pfks作为igfr途径的修饰剂和使用方法
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申请号： US11628557申请日： 2005-06-20
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公开(公告)号： US20090142272A1公开(公告)日： 2009-06-04
- 发明人: Lori S. Friedman , Helen Francis-Lang , Annette L. Parks , Kenneth James Shaw , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人： Lori S. Friedman , Helen Francis-Lang , Annette L. Parks , Kenneth James Shaw , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人地址： US CA South San Francisco
- 专利权人： Exelixis, Inc.
- 当前专利权人： Exelixis, Inc.
- 当前专利权人地址： US CA South San Francisco
- 国际申请： PCT/US05/21614 WO 20050620
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; C12Q1/68 ; C12N5/06 ; A61P43/00 ; G01N33/53
摘要：
Human PFK genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of PFK are provided.