An occlusive guidewire system having an ergonomic handheld control mechanism and torqueable kink-resistant guidewire having a distally located inflatable balloon. The present invention provides convenient structure and overall mechanism for operation of a torqueable kink-resistant guidewire, including evacuation and inflation control of an occlusive balloon, and sealing and severing of a crimpable inflation tube which is in communication with an occlusive balloon. The torqueable kink-resistant guidewire includes a centrally located shaft which imparts robustness to the torqueable kink-resistant guidewire. An inflation lumen aligns within the torqueable kink-resistant guidewire for inflation of the balloon.