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发明申请
US20090155280A1 Immunoglobulin Cleavage Fragments as Disease Indicators and Compositions for Detecting and Binding Such 审中-公开
免疫球蛋白切割片段作为疾病指标和组合物用于检测和结合

Immunoglobulin Cleavage Fragments as Disease Indicators and Compositions for Detecting and Binding Such
摘要：
The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions.
摘要（中）：

本发明涉及抗体组合物和该组合物用于检测与精制蛋白酶相关的疾病过程的用途。 试剂用于评估作为这种蛋白水解切割结果的IgG分解产物。 本发明还涉及治疗免疫特异性用于保持抗原结合但具有失去效应子功能的IgG分解产物的用途。

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