发明申请
US20090162348A1 GENETIC POLYMORPHISMS ASSOCIATED WITH PSORIASIS, METHODS OF DETECTION AND USES THEREOF
有权
与PSORIASIS相关的遗传多态性,检测方法及其用途
- 专利标题: GENETIC POLYMORPHISMS ASSOCIATED WITH PSORIASIS, METHODS OF DETECTION AND USES THEREOF
- 专利标题(中): 与PSORIASIS相关的遗传多态性,检测方法及其用途
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申请号: US12325832申请日: 2008-12-01
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公开(公告)号: US20090162348A1公开(公告)日: 2009-06-25
- 发明人: Yonghong LI , Ann BEGOVICH , Monica CHANG , Michele CARGILL , Steven SCHRODI
- 申请人: Yonghong LI , Ann BEGOVICH , Monica CHANG , Michele CARGILL , Steven SCHRODI
- 申请人地址: US CA Alameda
- 专利权人: CELERA CORPORATION
- 当前专利权人: CELERA CORPORATION
- 当前专利权人地址: US CA Alameda
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12Q1/68 ; A61P17/06 ; A61P37/00 ; G01N33/566
摘要:
The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
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