发明申请
US20090162377A1 Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
审中-公开
主要包含Gal2GlcNAc2Man3GlcNAc2糖型的免疫球蛋白
- 专利标题： Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
- 专利标题（中）： 主要包含Gal2GlcNAc2Man3GlcNAc2糖型的免疫球蛋白
-
申请号： US12284399申请日： 2008-09-22
-
公开(公告)号： US20090162377A1公开(公告)日： 2009-06-25
- 发明人: Tillman U. Gerngross , Huijuan Li , Stefan Wildt
- 申请人： Tillman U. Gerngross , Huijuan Li , Stefan Wildt
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12N5/16 ; A61P37/06
摘要：
The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is Gal2GlcNAc2Man3GlcNAc2 lacking fucose.
信息查询
