发明申请
- 专利标题： VACCINE FOR RSV AND MPV
- 专利标题（中）： 疫苗用于RSV和MPV
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申请号： US12238130申请日： 2008-09-25
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公开(公告)号： US20090162395A1公开(公告)日： 2009-06-25
- 发明人: James E. Crowe, JR. , Hoyin Mok , Robert E. Johnston , John V. Williams , Nancy L. Davis
- 申请人： James E. Crowe, JR. , Hoyin Mok , Robert E. Johnston , John V. Williams , Nancy L. Davis
- 主分类号： A61K39/155
- IPC分类号： A61K39/155 ; C12N7/00
摘要：
The present invention is directed to alphavirus vectored vaccine contructs encoding paramyxovirus proteins that find use in the prevention of respiratory syncytial virus or human metapneumovirus infections. In particular, these vaccines induce cellular and humoral immune responses that inhibit RSV. Also disclosed are improved methods for producing alphavirus vectored paramyxovirus vaccines.