发明申请
US20090163503A1 SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
有权
作为激酶抑制剂活化的取代的吡咯并吡唑衍生物
- 专利标题： SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
- 专利标题（中）： 作为激酶抑制剂活化的取代的吡咯并吡唑衍生物
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申请号： US12096989申请日： 2006-12-06
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公开(公告)号： US20090163503A1公开(公告)日： 2009-06-25
- 发明人: Tiziano Bandiera , Andrea Lombardi Borgia , Sten Christian Orrenius , Ettore Perrone , Italo Beria , Daniele Fancelli , Arturo Galvani
- 申请人： Tiziano Bandiera , Andrea Lombardi Borgia , Sten Christian Orrenius , Ettore Perrone , Italo Beria , Daniele Fancelli , Arturo Galvani
- 申请人地址： IT Nerviano (MI)
- 专利权人： NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人： NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人地址： IT Nerviano (MI)
- 优先权： EP05111962.6 20051212
- 国际申请： PCT/EP06/69373 WO 20061206
- 主分类号： A61K31/5355
- IPC分类号： A61K31/5355 ; C07D403/14 ; C07D413/14 ; A61K31/497 ; A61P35/00
摘要：
Substituted pyrrolo-pyrazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with dysregulated protein kinase activity, like cancer.
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