发明申请
- 专利标题： CARBOXYL- OR HYDROXYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
- 专利标题（中）： 羧甲基或羟基取代的苯并咪唑衍生物
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申请号： US12331461申请日： 2008-12-10
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公开(公告)号： US20090163552A1公开(公告)日： 2009-06-25
- 发明人: Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
- 申请人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
- 优先权： EP07150351.0 20071221
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; C07D401/12 ; C07D401/14 ; A61P9/00 ; A61P25/28 ; A61P35/00 ; C07D235/16 ; A61K31/4439
摘要：
This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.
公开/授权文献
- US07816540B2 Carboxyl- or hydroxyl-substituted benzimidazole derivatives 公开/授权日：2010-10-19
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