发明申请
- 专利标题： AMORPHOUS METAXALONE AND AMORPHOUS DISPERSIONS THEREOF
- 专利标题（中）： 非晶元音和其他非对称分散体
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申请号： US12332795申请日： 2008-12-11
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公开(公告)号： US20090163561A1公开(公告)日： 2009-06-25
- 发明人: Keith Lorimer , Kevin Wayne Meyer , Tong Sun , Shawn Watson , Kurt R. Nielsen
- 申请人： Keith Lorimer , Kevin Wayne Meyer , Tong Sun , Shawn Watson , Kurt R. Nielsen
- 申请人地址： US PA Philadelphia
- 专利权人： URL Pharma, Inc.
- 当前专利权人： URL Pharma, Inc.
- 当前专利权人地址： US PA Philadelphia
- 主分类号： A61K31/421
- IPC分类号： A61K31/421 ; C07D263/24 ; A61P25/00
摘要：
The present invention provides various amorphous forms of the compound metaxalone (I), such as solid amorphous metaxalone and amorphous dispersions comprising metaxalone. The present invention further provides pharmaceutical compositions comprising these amorphous forms, and methods of their preparation. The present invention additionally provides methods of treating painful conditions (e.g., such as painful musculoskeletal conditions) comprising administering a therapeutically effective amount of any one of these amorphous forms to a subject in need thereof.
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