发明申请
US20090169570A1 METHODS AND AGENTS FOR IMPROVING TARGETING OF CD138 EXPRESSING TUMOR CELLS
有权
用于改善CD138表达肿瘤细胞靶向的方法和试剂
- 专利标题： METHODS AND AGENTS FOR IMPROVING TARGETING OF CD138 EXPRESSING TUMOR CELLS
- 专利标题（中）： 用于改善CD138表达肿瘤细胞靶向的方法和试剂
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申请号： US12342815申请日： 2008-12-23
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公开(公告)号： US20090169570A1公开(公告)日： 2009-07-02
- 发明人: Benjamin Daelken , Christoph Uherek , Kenneth Anderson , Teru Hideshima , Christoph Bruecher
- 申请人： Benjamin Daelken , Christoph Uherek , Kenneth Anderson , Teru Hideshima , Christoph Bruecher
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P35/00
摘要：
Disclosed are immunoconjugates having specificity for CD138 that diminish adhesion of CD138 expressing tumor cells to stroma cells and methods of using the same. This diminished adhesion renders the tumor cells not only susceptible to the immunoconjugate, but also to other agents, in particular cytotoxic agents.
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