发明申请
US20090170134A1 BIFUNCTIONAL AND TRIFUNCTIONAL NITRONE SPIN TRAPPING COMPOUNDS AND USES THEREOF
失效
双功能和功能性硝基螺旋捕获化合物及其用途
- 专利标题： BIFUNCTIONAL AND TRIFUNCTIONAL NITRONE SPIN TRAPPING COMPOUNDS AND USES THEREOF
- 专利标题（中）： 双功能和功能性硝基螺旋捕获化合物及其用途
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申请号： US12343975申请日： 2008-12-24
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公开(公告)号： US20090170134A1公开(公告)日： 2009-07-02
- 发明人: Micael Joel Hardy , Marcos Lopez , Balaraman Kalyanaraman , Neil Hogg , Olivier Ouari , Paul Tordo
- 申请人： Micael Joel Hardy , Marcos Lopez , Balaraman Kalyanaraman , Neil Hogg , Olivier Ouari , Paul Tordo
- 主分类号： G01N33/573
- IPC分类号： G01N33/573 ; C07D495/04 ; G01N33/68 ; G01N33/543 ; G01N33/00
摘要：
Methods and compositions for detecting free radicals, the compositions being spin trapping compounds comprising a nitrone having a detecting moiety and optionally having a targeting moiety for targeting the nitrone to an organ, a cell, an organelle or a molecule of interest for directly detecting free radicals, especially free radicals in biological samples.
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