发明申请
- 专利标题: Mutant bacterium belonging to the genus bacillus
- 专利标题(中): 属于杆菌属的突变细菌
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申请号: US10590275申请日: 2005-03-04
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公开(公告)号: US20090170154A1公开(公告)日: 2009-07-02
- 发明人: Keiji Endo , Katsuya Ozaki
- 申请人: Keiji Endo , Katsuya Ozaki
- 申请人地址: JP Chuo-ku, Tokyo
- 专利权人: KAO CORPORATION
- 当前专利权人: KAO CORPORATION
- 当前专利权人地址: JP Chuo-ku, Tokyo
- 优先权: JP2004-062852 20040305
- 国际申请: PCT/JP2005/003756 WO 20050304
- 主分类号: C12P21/00
- IPC分类号: C12P21/00 ; C12N1/21 ; C12N15/87
摘要:
The present invention provides a mutant Bacillus bacterium capable of enhancing productivity of proteins or polypeptides, a recombinant microorganism produced by introducing genes encoding heterologous proteins or polypeptides into the mutant Bacillus bacterium, and a method for producing proteins or polypeptides by use of the recombinant microorganism.A mutant Bacillus bacterium which has, on the genome or plasmid thereof, DNA having a promoter sequence which is recognized and transcribed specifically during the sporulation stage and which is ligated to an upstream end of a sigA gene or a gene equivalent thereto, a recombinant microorganism produced by introducing genes encoding heterologous proteins or polypeptides into the mutant Bacillus bacterium, and a method for producing proteins or polypeptides by use of the recombinant microorganism.
公开/授权文献
- US07855065B2 Mutant bacterium belonging to the genus Bacillus 公开/授权日:2010-12-21