发明申请
US20090170909A1 ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
有权
ALPHA KETOAMIDE化合物作为CYSTEINE PROTEASE抑制剂
- 专利标题: ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
- 专利标题(中): ALPHA KETOAMIDE化合物作为CYSTEINE PROTEASE抑制剂
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申请号: US12337596申请日: 2008-12-17
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公开(公告)号: US20090170909A1公开(公告)日: 2009-07-02
- 发明人: Michael Graupe , John O. Link , Michael G. Roepel
- 申请人: Michael Graupe , John O. Link , Michael G. Roepel
- 申请人地址: US CA Menlo Park
- 专利权人: Virobay, Inc.
- 当前专利权人: Virobay, Inc.
- 当前专利权人地址: US CA Menlo Park
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/164 ; A61P37/00 ; A61P29/00
摘要:
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
公开/授权文献
- US07696250B2 Alpha ketoamide compounds as cysteine protease inhibitors 公开/授权日:2010-04-13
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