发明申请
- 专利标题： Cefuroxime axetil granule and process for the preparation thereof
- 专利标题（中）： 头孢呋辛酯颗粒及其制备方法
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申请号： US10584919申请日： 2005-01-10
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公开(公告)号： US20090175952A1公开(公告)日： 2009-07-09
- 发明人: Jong Soo Woo , Hee Chul Chang , Hong Gi Yi
- 申请人： Jong Soo Woo , Hee Chul Chang , Hong Gi Yi
- 优先权： KR10-2004-0001597 20040109; KR10-2004-0067569 20040826
- 国际申请： PCT/KR05/00066 WO 20050110
- 主分类号： A61K31/546
- IPC分类号： A61K31/546 ; A61K9/16 ; A61P31/00
摘要：
A cefuroxime axetil granule composition comprising a non-crystalline cefuroxime axetil solid dispersion or a substantially amorphous cefuroxime axetil, sucrose fatty acid ester, methacrylic acid-ethylacrylate copolymer and a disintegrating agent has highly desirable performance characteristics in terms of masking the bitterness of cefuroxime axetil, as well as high bioavailability and stability of cefuroxime axetil, and thus, can be advantageously used for oral administration of cefuroxime axetil.
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