- 专利标题： Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
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申请号： US12246067申请日： 2008-10-06
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公开(公告)号： US20090176770A1公开(公告)日： 2009-07-09
- 发明人: Stephan Georg MUELLER , Klaus RUDOLF , Philipp LUSTENBERGER , Dirk STENKAMP , Alexander DREYER , Kirsten ARNDT , Henri DOODS , Gerhard SCHAENZLE , Marco SANTAGOSTINO , Fabio PALEARI
- 申请人： Stephan Georg MUELLER , Klaus RUDOLF , Philipp LUSTENBERGER , Dirk STENKAMP , Alexander DREYER , Kirsten ARNDT , Henri DOODS , Gerhard SCHAENZLE , Marco SANTAGOSTINO , Fabio PALEARI
- 申请人地址： DE Ingelheim
- 专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人地址： DE Ingelheim
- 优先权： DE102004015723 20040329
- 主分类号： A61K31/5513
- IPC分类号： A61K31/5513 ; C07D243/14 ; A61K31/4523 ; A61P25/06 ; C07D401/04
摘要：
The present invention relates to the CGRP antagonists of general formula wherein A, X, D, E, G, M, Q and R1 to R3 are defined as in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.
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