发明申请
US20090181984A1 NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVE AND ITS MEDICAL USE
失效
新的1,4-二氮杂双环[3.2.2]壬基吡啶衍生物及其医药用途
![NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVE AND ITS MEDICAL USE](/docs/US/2009-07-16/US20090181984A1/abs.jpg.600x600.jpg)
- 专利标题： NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVE AND ITS MEDICAL USE
- 专利标题（中）： 新的1,4-二氮杂双环[3.2.2]壬基吡啶衍生物及其医药用途
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申请号： US12299106申请日： 2007-05-29
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公开(公告)号： US20090181984A1公开(公告)日： 2009-07-16
- 发明人: Dan Peters , Gunnar M. Olsen , Elsebet Ostergaard Nielsen , Daniel B. Timmermann , Steven Charles Loechel
- 申请人： Dan Peters , Gunnar M. Olsen , Elsebet Ostergaard Nielsen , Daniel B. Timmermann , Steven Charles Loechel
- 优先权： DKPA200600730 20060530
- 国际申请： PCT/EP2007/055171 WO 20070529
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D403/02 ; A61P25/30
![NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVE AND ITS MEDICAL USE](/abs-image/US/2009/07/16/US20090181984A1/abs.jpg.150x150.jpg)
摘要：
This invention relates to a novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its use in the manufacture of pharmaceutical compositions. The compound of the invention is found to be a cholinergic ligand at the nicotinic acetylcholine receptors.Due to its pharmacological profile the compound of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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