发明申请
- 专利标题： Ion Channel
- 专利标题（中）： 离子通道
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申请号： US11926693申请日： 2007-10-29
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公开(公告)号： US20090187996A1公开(公告)日： 2009-07-23
- 发明人: Nicola Brice , Mark Carlton , John Dixon , Isabelle Malinge , Dirk Zahn
- 申请人： Nicola Brice , Mark Carlton , John Dixon , Isabelle Malinge , Dirk Zahn
- 优先权： GBPCT/GB2005/001620 20050428; GB0510164.7 20050518
- 主分类号： G01N33/483
- IPC分类号： G01N33/483 ; G01N33/68 ; A61K49/00 ; C12Q1/68 ; A01K67/027 ; A01K67/00 ; C07K14/47 ; A61K39/395
摘要：
The present invention relates to a method of identifying a molecule suitable for the treatment, prophylaxis or alleviation of pain, the method comprising determining whether a candidate molecule is an agonist or antagonist, including a opener, blocker or modulator, of Kv9.2 polypeptide, in which the Kv9.2 polypeptide comprises the amino acid sequence shown in SEQ ID NO:3 or SEQ ID NO:5, or a sequence which is at least 90% identical thereto.
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