发明申请
US20090194693A1 Imaging Apparatus for Combined Temperature and Luminescence Spatial Imaging of an Object
审中-公开
用于物体的组合温度和发光空间成像的成像装置
- 专利标题: Imaging Apparatus for Combined Temperature and Luminescence Spatial Imaging of an Object
- 专利标题(中): 用于物体的组合温度和发光空间成像的成像装置
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申请号: US12301642申请日: 2007-05-14
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公开(公告)号: US20090194693A1公开(公告)日: 2009-08-06
- 发明人: Derk Jan Wilfred Klunder , Aleksey Kolesnychenko
- 申请人: Derk Jan Wilfred Klunder , Aleksey Kolesnychenko
- 申请人地址: NL EINDHOVEN
- 专利权人: KONINKLIJKE PHILIPS ELECTRONICS N.V.
- 当前专利权人: KONINKLIJKE PHILIPS ELECTRONICS N.V.
- 当前专利权人地址: NL EINDHOVEN
- 优先权: EP06114486.1 20060524
- 国际申请: PCT/IB2007/051813 WO 20070514
- 主分类号: G01N21/64
- IPC分类号: G01N21/64 ; G01N21/76
摘要:
An imaging apparatus is disclosed for combined temperature and luminescence spatial imaging of an object (1), such as a bio-array for detection of biological molecules. Light (5) is separated into a first (10) and a second (20) optical path, where the first optical path (10) guides infrared (IR), and the second optical path (20) guides luminescence light, preferably fluorescence light, from the object (1). Image intensifying means (30) converts infrared light (10a) in the first optical path into intensified light (10b), preferably visible light. Photo detection means (100) are arranged for spatial imaging of the object (1), the photo detection means being arranged for alternately receiving light from the first (10) and the second (20) optical path. Processing means (200) are capable of combining a temperature image (11) with a luminescence image (21) so as to obtain a combined image (25) of the object with a direct spatial correspondence between the two images. For bio-arrays this provides many advantages in relation to combined imaging of an array, whereupon numerous probe molecules are located.
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