发明申请
US20090203614A1 USE OF AGENTS THAT PREVENT THE GENERATION OF AMYLOID-LIKE PROTEINS AND/OR DRUSEN, AND/OR USE OF AGENTS THAT PROMOTE SEQUESTRATION AND/OR DEGRADATION OF, AND/OR PREVENT THE NEUROTOXIC EFFECTS OF SUCH PROTEINS IN THE TREATMENT OF MACULAR DEGENERATION
审中-公开
使用预防氨基酸样蛋白和/或DRUSEN的产生和/或使用促进序列和/或降解和/或预防这些蛋白质在治疗谷物变性中的神经毒性作用的药剂
- 专利标题： USE OF AGENTS THAT PREVENT THE GENERATION OF AMYLOID-LIKE PROTEINS AND/OR DRUSEN, AND/OR USE OF AGENTS THAT PROMOTE SEQUESTRATION AND/OR DEGRADATION OF, AND/OR PREVENT THE NEUROTOXIC EFFECTS OF SUCH PROTEINS IN THE TREATMENT OF MACULAR DEGENERATION
- 专利标题（中）： 使用预防氨基酸样蛋白和/或DRUSEN的产生和/或使用促进序列和/或降解和/或预防这些蛋白质在治疗谷物变性中的神经毒性作用的药剂
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申请号： US12425774申请日： 2009-04-17
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公开(公告)号： US20090203614A1公开(公告)日： 2009-08-13
- 发明人: Najam A. Sharif
- 申请人： Najam A. Sharif
- 申请人地址： CH Hunenberg
- 专利权人： ALCON, INC.
- 当前专利权人： ALCON, INC.
- 当前专利权人地址： CH Hunenberg
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61P27/02
摘要：
The present invention provides compositions and methods for treating age-related macular degeneration (AMD). More specifically, the methods of the invention target amyloid proteins and drusen that tend to accumulate in the eyes of those patients suffering from AMD. AMD is treated in the methods of the invention by providing agents that sequester and/or degrade such amyloid deposits and/or drusen such that a patient's vision is improved or restored.
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