发明申请
- 专利标题： COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE
- 专利标题（中）： 非抑制抑制剂的化合物及其使用方法
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申请号： US11577192申请日： 2005-10-13
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公开(公告)号： US20090203752A1公开(公告)日： 2009-08-13
- 发明人: Jeffrey A. Campbell , Atiyya Kahn , James Takasugi , Ellen Welch
- 申请人： Jeffrey A. Campbell , Atiyya Kahn , James Takasugi , Ellen Welch
- 申请人地址： US NJ South Plainfield
- 专利权人： PTC THERAPEUTICS, INC.
- 当前专利权人： PTC THERAPEUTICS, INC.
- 当前专利权人地址： US NJ South Plainfield
- 国际申请： PCT/US2005/037052 WO 20051013
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; A61P37/00 ; A61P9/00 ; A61P25/00 ; A61P11/00 ; A61P35/00 ; C07D271/06
摘要：
The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
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